Lance Price TabsBio Lance Price is a Professor at the George Washington University’s Milken Institute School of Public Health in Washington DC. He is also the founding director of the Antibiotic Resistance Action Center. Dr. Price works at the interface between science and policy to address the growing crisis of antibiotic resistance. In the laboratory, Dr. Price uses cutting-edge molecular approaches to trace the origins of antibiotic-resistant bacteria and develop strategies to block their transmission. In the policy arena, Dr. Price works with non-governmental organizations and policymakers to develop science-based policies to curb antibiotic abuse in food-animal production. Dr. Price’s works has been covered in media outlets around the world. Dr. Price has a Bachelor’s and Master’s Degree from the Department of Biology at Northern Arizona University and a PhD from the Johns Hopkins Bloomberg School of Public Health. ExpertiseExpertise: Environmental Health PolicyEducation: Bachelor of Science (Microbiology), Northern Arizona University, 1994 Master of Science (Biology), Northern Arizona University, 2000 Doctor of Philosophy (Environmental Health Sciences), Johns Hopkins University, 2006 Community Service: Dr. Price periodically serves as a reviewer for the journals BMC Infectious Diseases, Clinical Microbiology and Infection, Emerging Infectious Diseases, Environmental Health Perspectives, Genome Research, MBio, and PLoS ONE. He serves as an external partner of the National Food Institute of Denmark's Center for Genomic Epidemiology. ResearchResearch: Dr. Price's current research interests include livestock-associated MRSA, foodborne urinary tract infections, and the role of the human microbiome in health and disease. He has received research funding from the National Institute of Allergy and Infectious Diseases (RO1), National Science Foundation, Canadian Institutes of Health Research, US Army Medical Research and Material Command, and Pew Charitable Trust, among others. PublicationsPublications: Greater ciprofloxacin tolerance as a possible selectable phenotype underlying the pandemic spread of the H30 subclone of Escherichia coli sequence type 131. Johnson JR, Porter SB, Thuras P, Johnson TJ, Price LB, Tchesnokova V, Sokurenko EV. Antimicrob Agents Chemother . 2015;59(11):7132-5. PMID: 26601194; PMCID: PMC4640600 Industrial food animal production and community health. Casey JA, Kim BF, Larsen J, Price LB, Nachman KE. Curr Environ Health Rep. 2015;2(3):259-71. Meticillin-resistant Staphylococcus aureus CC398 is an increasing cause of disease in people with no livestock contact in Denmark, 1999 to 2011. Larsen J, Petersen A, Soerum M, Stegger M, van Alphen L, Valentiner-Branth P, Knudsen LK, Larsen LS, Feingold B, Price LB, Andersen PS, Larsen AR, Skov RL. Euro Surveill. 2015;20(37). PMID: 26535590; PMCID: PMC4902279 Using Whole Genome Analysis to Examine Recombination across Diverse Sequence Types of Staphylococcus aureus. Driebe EM, Sahl JW, Roe C, Bowers JR, Schupp JM, Gillece JD, Kelley E, Price LB, Pearson TR, Hepp CM, Brzoska PM, Cummings CA, Furtado MR, Andersen PS, Stegger M, Engelthaler DM, Keim PS. PLoS One. 2015 Jul 10;10(7):e0130955. PMID: 26161978; PMCID: PMC4498916. Penile microbiota and female partner bacterial vaginosis in Rakai, Uganda. Liu CM, Hungate BA, Tobian AA, Ravel J, Prodger JL, Serwadda D, Kigozi G, Galiwango RM, Nalugoda F, Keim P, Wawer MJ, Price LB, Gray RH. MBio. 16;6(3). PMID: 26081632; PMCID: PMC4471566. A framework to reduce infectious disease risk from urban poultry in the United States. Tobin MR, Goldshear JL, Price LB, Graham JP, Leibler JH. Public Health Rep. 2015;130(4):380-91. PMID: 26346104; PMCID: PMC4547567 Intermingled Klebsiella pneumoniae populations between retail meats and human urinary tract infections. Davis GS, Waits K, Nordstrom L, Weaver B, Aziz M, Gauld L, Grande H, Bigler R, Horwinski J, Porter S, Marc Stegger M, Johnson JR, Liu CM, Price LB. Clin Infect Disease. 2015;61(6), pp.892-899. PMCID: PMC4551003 Linking soil bacterial biodiversity and soil carbon stability. Mau RL, Liu CM, Aziz M, Schwartz E, Dijkstra P, Marks JC, Price LB, Keim P, Hungate BA. ISME J. 2014 June 23. PMID: 25350158; PMCID: PMC4438316 Staphylococcus aureus and the Ecology of the Nasal Microbiome. Science Advances. Liu CM, Price LB, Hungate, BA, Abraham A, Larsen LA, Christensen K, Stegger M, Skov R, Andersen PS. 2015 June 5. 1:e1400216. PMID: 26601194; PMCID: PMC4640600 Ominous projections for global antibiotic use in food animal productions (invited Commentary). Price LB, Koch BJ, Hungate BA. Proc Nat Acad Sci. 2015 May 5;112(18):5554-5. Epub 2015 Apr 28. PMID: 25922534; PMCID: PMC4426449. Complete Genome Sequence of a Carbapenem-Resistant Extraintestinal Pathogenic Escherichia coli Strain Belonging to the Sequence Type 131 H30R Subclade. Johnson TJ, Hargreaves M, Shaw K, Snippes P, Lynfield R, Aziz M, Price LB. Genome Announc. 2015 Apr 9;3(2). pii: e00272-15. doi: 10.1128/genomeA.00272-15. PMID: 25858844; PMCID: PMC4392156. An exploratory study of dog park visits as a risk factor for exposure to drug-resistant extra-intestinal pathogenic E. coli (ExPEC). Ahmed LN, Price LB, Graham JP. BMC Res Notes. 2015 Apr 10;8:137. doi: 10.1186/s13104-015-1103-2. PMID: 25886556; PMCID: PMC4397871. Quantitative microbial ecology through stable isotope probing. Hungate BA, Mau RL, Schwartz E, Gregory Caporaso J, Dijkstra P, van Gestel N, Koch BJ, Liu CM, McHugh TA, Marks JC, Morrissey EM, Price LB. Appl Environ Microbiol. 2015;81(21):7570-81. PMID: 26296731; PMCID: PMC4592864 Impact of saline irrigation and topical corticosteroids on the postsurgical sinonasal microbiota. Liu CM, Kohanski MA, Mendiola M, Soldanova K, Dwan MG, Lester R, Nordstrom L, Price LB, Lane AP. Int Forum Allergy Rhinol. 2015 Mar;5(3):185-90. doi: 10.1002/alr.21467. Epub 2014 Dec 29. PMID: 25556553; PMCID: PMC4628778 Evidence for Human Adaptation and Foodborne Transmission of Livestock-Associated Methicillin-Resistant Staphylococcus aureus. Larsen J, Stegger M, Andersen PS, Petersen A, Larsen AR, Westh H, Agersø Y, Fetsch A, Kraushaar B, Käsbohrer A, Feβler AT, Schwarz S, Cuny C, Witte W, Butaye P, Denis O, Haenni M, Madec JY, Jouy E, Laurent F, Battisti A, Franco A, Alba P, Mammina C, Pantosti A, Monaco M, Wagenaar JA, de Boer E, van Duijkeren E, Heck M, Domínguez L, Torres C, Zarazaga M, Price LB, Skov RL. Clin Infect Dis. 2016 Nov 15;63(10):1349-1352. PubMed PMID: 27655995; PubMed Central PMCID: PMC5091345. Household Clustering of Escherichia coli Sequence Type 131 Clinical and Fecal Isolates According to Whole Genome Sequence Analysis. Johnson JR, Davis G, Clabots C, Johnston BD, Porter S, DebRoy C, Pomputius W, Ender PT, Cooperstock M, Slater BS, Banerjee R, Miller S, Kisiela D, Sokurenko EV, Aziz M, Price LB. Open Forum Infect Dis. 2016 Jun 16;3(3):ofw129. PubMed PMID: 27703993; PubMed Central PMCID: PMC5047392. Genital Anaerobic Bacterial Overgrowth and the PrePex Male Circumcision Device, Rakai, Uganda. Liu CM, Prodger JL, Tobian AA, Serwadda D, Galiwango RM, Nalugoda F, Kighoma N, Mwinike J, Anyokorit M, Price LB, Wawer MJ, Kigozi G, Gray RH. J Infect Dis. 2016 Aug 15;214(4):595-8. doi: 10.1093/infdis/jiw182. PubMed PMID: 27190185; PubMed Central PMCID: PMC4957438. Separate F-Type Plasmids Have Shaped the Evolution of the H30 Subclone of Escherichia coli Sequence Type 131. Johnson TJ, Danzeisen JL, Youmans B, Case K, Llop K, Munoz-Aguayo J, Flores-Figueroa C, Aziz M, Stoesser N, Sokurenko E, Price LB, Johnson JR. mSphere. 2016 Jun 29;1(4). PMID: 27390780; PMCID: PMC4933990 Recent Research Examining Links Among Klebsiella pneumoniae from Food, Food Animals, and Human Extraintestinal Infections. Davis GS, Price LB. Curr Environ Health Rep. 2016 Jun;3(2):128-35. PMID: 27022987 Complete Genome Sequence of a CTX-M-15-Producing Escherichia coli Strain from the H30Rx Subclone of Sequence Type 131 from a Patient with Recurrent Urinary Tract Infections, Closely Related to a Lethal Urosepsis Isolate from the Patient's Sister. Johnson TJ, Aziz M, Liu CM, Sokurenko E, Kisiela DI, Paul S, Andersen P, Johnson JR, Price LB. Genome Announc. 2016 May 12;4(3). PMID: 27174264; PMCID: PMC4866839 Phylogenetic organization of bacterial activity. I Morrissey EM, Mau RL, Schwartz E, Caporaso JG, Dijkstra P, van Gestel N, Koch BJ, Liu CM, Hayer M, McHugh TA, Marks JC, Price LB, Hungate BA. SME J. 2016 Mar 4. PMID: 26943624 Evolutionary history of the global emergence of the Escherichia coli epidemic clone ST131. Stoesser N, Sheppard AE, Pankhurst L, de Maio N, Moore CE, Sebra R, Turner P, Anson LW, Kasarskis A, Batty EM, Kos V, Wilson DJ, Phetsouvanh R, Wyllie D, Sokurenko E, Manges AR, Johnson TJ, Price LB, Peto TEA, Johnson JR, Didelot X, Sarah Walker A, Crook DW. MBio. 2016;7(2) PMCID: PMC4807372 The Influence of Time and Plant Species on the Composition of the Decomposing Bacterial Community in a Stream Ecosystem. Wymore AS, Liu CM, Hungate BA, Schwartz E, Price LB, Whitham TG, Marks JC. Microb Ecol. 2016 May;71(4):825-34. PMID: 26879940 Staphylococcus aureus nasal carriage among beefpacking workers in a midwestern united states slaughterhouse. Leibler JH, Jordan JA, Brownstein K, Lander L, Price LB, Perry MJ. PLoS ONE. 2016;11(2). PMCID: PMC4750916 Animal production and antimicrobial resistance in the clinic. Robinson TP, Wertheim HFL, Kakkar M, Kariuki S, Bu D, Price LB. Lancet. 2016;387(10014):e1-3. PMID: 26603925 Clonal dissemination of Enterobacter cloacae harboring blaKPC-3 in the upper midwestern united states. Hargreaves ML, Shaw KM, Dobbins G, Vagnone PMS, Harper JE, Boxrud D, Lynfield R, Aziz M, Price LB, Silverstein KAT, Danzeisen JL, Youmans B, Case K, Sreevatsan S, Johnson TJ. Antimicrob Agents Chemother. 2015;59(12):7723-34. PMID: 26438492; PMCID: PMC4649179 The semen microbiome and its relationship with local immunology and viral load in HIV infection. Liu CM, Osborne BJ, Hungate BA, Shahabi K, Huibner S, Lester R, Dwan MG, Kovacs C, Contente-Cuomo TL, Benko E, Aziz M, Price LB, Kaul R. PLoS Pathog. 2014 Jul 24;10(7):e1004262. doi: 10.1371/journal.ppat.1004262. eCollection 2014 Jul. A case control study of environmental and occupational exposures associated with methicillin resistant Staphylococcus aureus nasal carriage in patients admitted to a rural tertiary care hospital in a high density swine region. Schinasi L, Wing S, Augustino KL, Ramsey KM, Nobles DL, Richardson DB, Price LB, Aziz M, MacDonald PD, Stewart JR. Environ Health. 2014 Jun 23;13(1):54. doi: 10.1186/1476-069X-13-54. Origin and evolution of European community-acquired methicillin-resistant Staphylococcus aureus. Stegger M, Wirth T, Andersen PS, Skov RL, De Grassi A, Simões PM, Tristan A, Petersen A, Aziz M, Kiil K, Cirkovic I, Udo EE, del Campo R, Vuopio-Varkila J, Ahmad N, Tokajian S, Peters G, Schaumburg F, Olsson-Liljequist B, Givskov M, Driebe EE, Vigh HE, Shittu A, Ramdani-Bougessa N, Rasigade JP, Price LB, Vandenesch F, Larsen AR, Laurent F. MBio. 2014 Aug 26;5(5):e01044-14. doi: 10.1128/mBio.01044-14. Multidrug-Resistant and Methicillin-Resistant Staphylococcus aureus (MRSA) in Hog Slaughter and Processing Plant Workers and Their Community in North Carolina (USA). Castillo Neyra R, Frisancho JA, Rinsky JL, Resnick C, Carroll KC, Rule AM, Ross T, You Y, Price LB, Silbergeld EK.Multidrug-Resistant and Methicillin-Resistant Staphylococcus aureus (MRSA) in Hog Slaughter and Processing Plant Workers and Their Community in North Carolina (USA). Environ Health Perspect. 2014 Feb 7. [Epub ahead of print] High prevalence and two dominant host-specific genotypes of Coxiella burnetii in U.S. milk. Pearson T, Hornstra HM, Hilsabeck R, Gates LT, Olivas SM, Birdsell DM, Hall CM, German S, Cook JM, Seymour ML, Priestley RA, Kondas AV, Clark Friedman CL, Price EP, Schupp JM, Liu CM, Price LB, Massung RF, Kersh GJ, Keim P.High prevalence and two dominant host-specific genotypes of Coxiella burnetii in U.S. milk.BMC Microbiol. 2014 Feb 17;14(1):41. doi: 10.1186/1471-2180-14-41. The semen microbiome and its relationship with local immunology and viral load in HIV infection. Liu CM, Osborne BJ, Hungate BA, Shahabi K, Huibner S, Lester R, Dwan MG, Kovacs C, Contente-Cuomo TL, Benko E, Aziz M, Price LB, Kaul R. PLoS Pathog. 2014 Jul 24;10(7):e1004262. doi: 10.1371/journal.ppat.1004262. eCollection 2014 Jul. A case control study of environmental and occupational exposures associated with methicillin resistant Staphylococcus aureus nasal carriage in patients admitted to a rural tertiary care hospital in a high density swine region. Schinasi L, Wing S, Augustino KL, Ramsey KM, Nobles DL, Richardson DB, Price LB, Aziz M, MacDonald PD, Stewart JR. Environ Health. 2014 Jun 23;13(1):54. doi: 10.1186/1476-069X-13-54. Origin and evolution of European community-acquired methicillin-resistant Staphylococcus aureus. Stegger M, Wirth T, Andersen PS, Skov RL, De Grassi A, Simões PM, Tristan A, Petersen A, Aziz M, Kiil K, Cirkovic I, Udo EE, del Campo R, Vuopio-Varkila J, Ahmad N, Tokajian S, Peters G, Schaumburg F, Olsson-Liljequist B, Givskov M, Driebe EE, Vigh HE, Shittu A, Ramdani-Bougessa N, Rasigade JP, Price LB, Vandenesch F, Larsen AR, Laurent F. MBio. 2014 Aug 26;5(5):e01044-14. doi: 10.1128/mBio.01044-14. Prevalence of antibiotic-resistant E. coli in retail chicken: comparing conventional, organic, kosher, and raised without antibiotics. Millman JM, Waits K, Grande H, Marks AR, Marks JC, Price LB, Hungate BA.2013 Jul;155 (4). Complete Genome Sequence of the Epidemic and Highly Virulent CTX-M-15-Producing H30-Rx Subclone of Escherichia coli ST131. Andersen PS, Stegger M, Aziz M, Contente-Cuomo T, Gibbons HS, Keim P, Sokurenko EV, Johnson JR, Price LB.Complete Genome Sequence of the Epidemic and Highly Virulent CTX-M-15-Producing H30-Rx Subclone of Escherichia coli ST131. Genome Announc. 2013 Dec 5;1(6). pii: e00988-13. doi: 10.1128/genomeA.00988-13. Rapid differentiation between livestock-associated and livestock-independent Staphylococcus aureus CC398 clades. Stegger M1, Liu CM, Larsen J, Soldanova K, Aziz M, Contente-Cuomo T, Petersen A, Vandendriessche S, Jiménez JN, Mammina C, van Belkum A, Salmenlinna S, Laurent F, Skov RL, Larsen AR, Andersen PS, Price LB.Vandendriessche S, Jiménez JN, Mammina C, van Belkum A, Salmenlinna S, Laurent F, Skov RL, Larsen AR, Andersen PS, Price LB. PLoS One. 2013 Nov 14;8(11):e79645. doi: 10.1371/journal.pone.0079645. eCollection 2013. Staphylococcus aureus CC398: host adaptation and emergence of methicillin resistance in livestock Price LB, Stegger M, Hasman H, Aziz M, Larsen J, Andersen PS, Pearson T, Waters AE, Foster JT, Schupp J, Gillece J, Driebe E, Liu CM, Springer B, Zdovc I, Battisti A, Franco A, Zmudzki J, Schwarz S, Butaye P, Jouy E, Pomba C, Porrero MC, Ruimy R, Smith TC, Robinson DA, Weese JS, Arriola CS, Yu F, Laurent F, Keim P, Skov R, Aarestrup FM. Staphylococcus aureus CC398: host adaptation and emergence of methicillin resistance in livestock. MBio. 2012 Feb 21;3(1). pii: e00305-11. doi: 10.1128/mBio.00305-11. Print 2012. Genotyping of Brucella species using clade specific SNPs Foster JT, Price LB, Beckstrom-Sternberg SM, Pearson T, Brown WD, Kiesling DM, Allen CA, Liu CM, Beckstrom-Sternberg J, Roberto FF, Keim P. Genotyping of Brucella species using clade specific SNPs. BMC Microbiol. 2012 Jun 19;12:110. BactQuant: An enhanced broad-coverage bacterial quantitative real-time PCR assay Liu CM, Aziz M, Kachur S, Hsueh PR, Huang YT, Keim P, Price LB. BactQuant: An enhanced broad-coverage bacterial quantitative real-time PCR assay. BMC Microbiol. 2012 Apr 17;12(1):56. [Epub ahead of print] Molecular and phenotypic characteristics of healthcare- and community-associated methicillin-resistant Staphylococcus aureus at a rural hospital Peterson AE, Davis MF, Julian KG, Awantang G, Greene WH, Price LB, Waters A, Doppalapudi A, Krain LJ, Nelson K, Silbergeld EK, Whitener CJ. Molecular and phenotypic characteristics of healthcare- and community-associated methicillin-resistant Staphylococcus aureus at a rural hospital. PLoS One. 2012;7(6):e38354. Epub 2012 Jun 15. Genome sequence of Staphylococcus aureus strain 11819-97, an ST80-IV European community-acquired methicillin-resistant isolate Stegger M, Price LB, Larsen AR, Gillece JD, Waters AE, Skov R, Andersen PS. Genome sequence of Staphylococcus aureus strain 11819-97, an ST80-IV European community-acquired methicillin-resistant isolate. J Bacteriol. 2012 Mar;194(6):1625-6. Dry collection and culture methods for recovery of methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains from indoor home environments Davis MF, Baron P, Price LB, Williams DL, Jeyaseelan S, Hambleton IR, Diette GB, Breysse PN, McCormack MC. Dry collection and culture methods for recovery of methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains from indoor home environments. Appl Environ Microbiol. 2012 Apr;78(7):2474-6. Epub 2012 Jan 27. Population genetics of Vibrio cholerae from Nepal in 2010: evidence on the origin of the Haitian outbreak Hendriksen RS, Price LB, Schupp JM, Gillece JD, Kaas RS, Engelthaler DM, Bortolaia V, Pearson T, Waters AE, Upadhyay BP, Shrestha SD, Adhikari S, Shakya G, Keim PS, Aarestrup FM. Population genetics of Vibrio cholerae from Nepal in 2010: evidence on the origin of the Haitian outbreak. MBio. 2011 Sep 1;2(4):e00157-11. doi: 10.1128/mBio.00157-11. Print 2011. Prevalence of potentially neuropathic Campylobacter jejuni strains on commercial broiler chicken products Hardy CG, Lackey LG, Cannon J, Price LB, Silbergeld EK. Prevalence of potentially neuropathic Campylobacter jejuni strains on commercial broiler chicken products. Int J Food Microbiol. 2011 Feb 28;145(2-3):395-9. Epub 2011 Jan 8. Molecular investigations of a locally acquired case of melioidosis in Southern AZ, USA Engelthaler DM, Bowers J, Schupp JA, Pearson T, Ginther J, Hornstra HM, Dale J, Stewart T, Sunenshine R, Waddell V, Levy C, Gillece J, Price LB, Contente T, Beckstrom-Sternberg SM, Blaney DD, Wagner DM, Mayo M, Currie BJ, Keim P, Tuanyok A. Molecular investigations of a locally acquired case of melioidosis in Southern AZ, USA. PLoS Negl Trop Dis. 2011 Oct;5(10):e1347. Epub 2011 Oct 18. An ecological perspective on U.S. industrial poultry production: the role of anthropogenic ecosystems on the emergence of drug-resistant bacteria from agricultural environments Davis MF, Price LB, Liu CM, Silbergeld EK. An ecological perspective on U.S. industrial poultry production: the role of anthropogenic ecosystems on the emergence of drug-resistant bacteria from agricultural environments. Curr Opin Microbiol. 2011 Jun;14(3):244-50. Epub 2011 May 27. Review. The otologic microbiome: a study of the bacterial microbiota in a pediatric patient with chronic serous otitis media using 16SrRNA gene-based pyrosequencing Liu CM, Cosetti MK, Aziz M, Buchhagen JL, Contente-Cuomo TL, Price LB, Keim PS, Lalwani AK. The otologic microbiome: a study of the bacterial microbiota in a pediatric patient with chronic serous otitis media using 16SrRNA gene-based pyrosequencing. Arch Otolaryngol Head Neck Surg. 2011 Jul;137(7):664-8. Multidrug-Resistant Staphylococcus aureus in US Meat and Poultry Waters AE, Contente-Cuomo T, Buchhagen J, Liu CM, Watson L, Pearce K, Foster JT, Bowers J, Driebe EM, Engelthaler DM, Keim PS, Price LB. Multidrug-Resistant Staphylococcus aureus in US Meat and Poultry. Clin Infect Dis. 2011 May;52(10):1227-30. Epub 2011 Apr 15.
